The class of drug is an antidote against Western Disease, addiction, etc by patching a reward center. Turns out refined sugar, HFCS, and such are poison.
>> By knocking out Slc2a4 and reducing glucose influx, the aged stem cells became more likely to activate and produce new neurons.
They knocked out a gene, it was not glucose alone. Please understand this before joining the new fad diet train.
Article in Nature link:
"One reason that mouse models might not completely mimic human disorders is that mice simply might not be capable of expressing some cognitive human disease symptoms that are apparent to the observer. For example, Huntington's disease patients show dyskinesia (involuntary movements), whereas mice do not."
https://www.nature.com/scitable/topicpage/the-use-of-animal-...
Please, show me a single credible scientific study that recommends increasing or even holding steady our current levels of sugar consumption. Until then, I will listen to the research and reduce sugar. If it promotes new neuron growth, that's gravy on top but really beside the point.
I did a 5 year stint of no sugar except for one cheat day a month.
My rules were: Fruit and milk OK No products with honey, sugar, high fructose corn syrup etc.
The first 2 weeks are the hardest then it is pretty easy to do...
"Once upon a time, sugar was a condiment. Now it’s a diet staple. That’s a problem, because as it turns out, we as human beings have a limited capacity to metabolize it. There are things you can do to up your metabolism, like vigorous exercise. But the bottom line is we have a limited capacity to metabolize it — virtually like every poison, kind of like alcohol. So a little is okay; a lot is not."
[0] https://www.vox.com/2014/6/2/5771008/the-case-for-treating-s...